Mr Christos Tolias

Consultant Neurosurgeon

Year Qualified: 1989
Qualifications: MBBS, PhD, FRCS (Engl), FRCS (SN)
Specialty: Neurosurgery

Special Interests

Adult hydrocephalus
Adult spinal surgery
AVMs/cavernomas/AV fistulas
Cerebral aneurysms
Head injury
Spinal degenerative disease (neck pain, arm pain, back pain, sciatica)
Subarachnoid haemorrhage

Biography

Mr Tolias has been a Consultant Neurosurgeon at King’s College Hospital since 2005. He has a PhD in Biological Sciences from the University of Warwick, and extensive research experience in traumatic brain injury and the mechanisms of brain cell death. He undertook specialist training in Neurosurgery in Liverpool and Birmingham followed by a Clinical Fellowship in Richmond, Virginia, USA. He is the Lead Neurovascular Surgeon at King’s College Hospital and Clinical Lead in Neurosurgery.

He was the first surgeon in the UK to perform the non-occlusive cerebral vascular bypass technique. In addition to his expertise in degenerative spine disease, which includes the management of back and neck pain, arm pain and sciatica, he has specialist expertise in the management of neurovascular conditions (cerebral aneurysms, AVMs, cavernomas, AV fistulas), the surgical treatment of stroke (decompressive craniectomy and revascularisation for Moyamoya disease, sickle cell anaemia) and trauma. His expertise extends to the use of radiosurgery (CyberKnife and GammaKnife) for the treating these conditions.

Related services

Research

Choo MC, Tolias CM (2012) ‘Response to: a web-based referral system for neurosurgery–a solution to our problems?‘, British journal of neurosurgery, 26,(2):298
Demetriades AK, Tolias C (2011) ‘Lumbar drainage in aneurysmal subarachnoid haemorrhage‘, British journal of neurosurgery, 25,(4):537
Choo MC, Thennakon S, Shapey J, Tolias CM (2011) ‘A web-based referral system for neurosurgery–a solution to our problems?‘, British journal of neurosurgery, 25,(3):384-7
Feuerstein D, Manning A, Hashemi P, Bhatia R, Fabricius M, Tolias C, Pahl C, Ervine M, Strong AJ, Boutelle MG (2010) ‘Dynamic metabolic response to multiple spreading depolarizations in patients with acute brain injury: an online microdialysis study‘, Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism, 30,(7):1343-55
Crocker M, Walsh D, Epaliyanage P, Tolias CM (2010) ‘Excimer laser-assisted non-occlusive cerebral vascular Anastomosis (ELANA): review of the first UK experience‘, British journal of neurosurgery, 24,(2):148-55
Kumaria A, Tolias CM (2009) ‘Normobaric hyperoxia therapy for traumatic brain injury and stroke: a review‘, British journal of neurosurgery, 23,(6):576-84
Dreier JP, Major S, Manning A, Woitzik J, Drenckhahn C, Steinbrink J, Tolias C, Oliveira-Ferreira AI, Fabricius M, Hartings JA, Vajkoczy P, Lauritzen M, Dirnagl U, Bohner G, Strong AJ, COSBID study group (2009) ‘Cortical spreading ischaemia is a novel process involved in ischaemic damage in patients with aneurysmal subarachnoid haemorrhage‘, Brain : a journal of neurology, 132,(Pt 7):1866-81
Papadakos N, Georges H, Sibtain N, Tolias CM (2009) ‘Thoracic disc prolapse presenting with abdominal pain: case report and review of the literature‘, Annals of the Royal College of Surgeons of England, 91,(5):W4-6
Crocker M, Corns R, Hampton T, Deasy N, Tolias CM (2008) ‘Vascular neurosurgery following the International Subarachnoid Aneurysm Trial: modern practice reflected by subspecialization‘, Journal of neurosurgery, 109,(6):992-7
Kumaria A, Tolias CM, Burnstock G (2008) ‘ATP signalling in epilepsy‘, Purinergic signalling, 4,(4):339-46
Kumaria A, Tolias CM (2008) ‘In vitro models of neurotrauma‘, British journal of neurosurgery, 22,(2):200-6
Crocker M, Tolias C (2007) ‘What future for vascular neurosurgery?‘, Vascular health and risk management, 3,(3):243-4
Tolias CM, Reinert M, Seiler R, Gilman C, Scharf A, Bullock MR (2004) ‘Normobaric hyperoxia–induced improvement in cerebral metabolism and reduction in intracranial pressure in patients with severe head injury: a prospective historical cohort-matched study‘, Journal of neurosurgery, 101,(3):435-44
Tolias CM, Bullock MR (2004) ‘Critical appraisal of neuroprotection trials in head injury: what have we learned?‘, NeuroRx : the journal of the American Society for Experimental NeuroTherapeutics, 1,(1):71-9
Richards DA, Tolias CM, Sgouros S, Bowery NG (2003) ‘Extracellular glutamine to glutamate ratio may predict outcome in the injured brain: a clinical microdialysis study in children‘, Pharmacological research : the official journal of the Italian Pharmacological Society, 48,(1):101-9
Tolias CM, Richards DA, Bowery NG, Sgouros S (2002) ‘Extracellular glutamate in the brains of children with severe head injuries: a pilot microdialysis study‘, Child’s nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery, 18,(8):368-74
Tolias CM, Giovanni JV, Sgouros S, Hockley AD (2001) ‘Cerebral abscess associated with a pulmonary arteriovenous malformation in a patient suffering from alpha thalassaemia‘, Child’s nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery, 17,(4-5):283-5
Carmel JB, Galante A, Soteropoulos P, Tolias P, Recce M, Young W, Hart RP (2001) ‘Gene expression profiling of acute spinal cord injury reveals spreading inflammatory signals and neuron loss‘, Physiological genomics, 7,(2):201-13
Tolias CM, McNeil CJ, Kazlauskaite J, Hillhouse EW (1999) ‘Astrocytes rather than neurones mediate interleukin-1beta dependent nitric oxide and superoxide radical release in primary hypothalamic rat cell cultures‘, Neuroscience letters, 273,(1):57-60
Tolias CM, McNeil CJ, Kazlauskaite J, Hillhouse EW (1999) ‘Superoxide generation from constitutive nitric oxide synthase in astrocytes in vitro regulates extracellular nitric oxide availability‘, Free radical biology & medicine, 26,(1-2):99-106
Tolias CM, Beale DJ, Sakas DE (1997) ‘Giant lumbar meningioma: a common tumour in an unusual location‘, Neuroradiology, 39,(4):276-7