Thrombosis and haemostasis
What we do
Our service leads the UK in the diagnosis, treatment and prevention of venous thromboembolism (VTE).
We diagnose and treat conditions including:
- venous thrombosis such as deep vein thrombosis (DVT) and pulmonary embolism (PE)
- thrombophilias including genetic thrombophilia and acquired conditions such as antiphospholipid syndrome (APS)
- thrombocytosis, thrombocytopaenia and polycythaemia.
- suspected bleeding disorders.
We offer fast assessment of patients with suspected DVTs, usually seeing them the day they are referred. We aim to make a diagnosis within two hours and have patients needing treatment home within four hours.
As part of our high-quality, patient-centred service, we have an extensive research programme. Current projects include:
- improving outcomes after DVT
- examining how thrombophilia (a condition where blood clots too easily) affects miscarriage
- learning the lessons from thrombosis brought on by hospital stays.
Location
Ground floor, Cheyne Wing, King’s College Hospital, Denmark Hill, London, SE5 9RS
Contact Details
- Anticoagulation Clinic tel: 020 3299 5553
- Anticoagulation Clinic email: [email protected]
Frequently asked questions about anticoagulants
1. For all patients on anticoagulants (also known as blood thinners)
Will I bleed if I take an anticoagulant?
When you take anticoagulants, your blood will not clot as easily and you may find that you bleed more than normal. You may notice that when you cut yourself, you bleed a little longer. Nosebleeds, bleeding gums and heavier periods are all more likely when you take anticoagulants. Continue to take your anticoagulant and contact the clinic if you experience any of these or something else you are concerned about. Find out more information about periods and anticoagulation.
I noticed some blood in my urine, poo and/or unusual bruising. What should I do?
If you notice any blood in your urine or poo or black poo, you must seek medical attention. If you develop any bruises that appear without any obvious cause, or if the bruising spreads, feels hard or darker and more painful, please seek medical attention.
Attend the nearest emergency department if you experience any of the following:
- nosebleeds lasting longer than 15 minutes
- blood when coughing or vomiting
- if you hit your head, face or tummy (abdomen) or experience severe headaches
- if you experience any serious bleeding that does not stop or slow down with first aid measures such as applying pressure and raising the affected area
Any symptoms of serious bleeding must be treated urgently
What if I need to have surgery or a procedure?
Please contact your anticoagulation clinic as soon as possible. Your anticoagulant medication may need to be paused before surgery. We usually require two weeks’ notice ahead of the surgery to create a personalised plan for you.
What if I need to have dental work?
It is important to let your dentist know you are taking anticoagulants before any dental procedure, due to the risk of bleeding. You may need to have a blood test before starting treatment.
Can I travel abroad?
It is safe to travel while on anticoagulants. Please ensure you take enough supply of medication for the duration of your trip. If you take warfarin or acenocoumarol, take your dosing slip with you in case you need to have a test or need treatment while abroad. In addition, please inform your anticoagulation clinic when you are travelling and how long you will be away for. The clinic will advise if you need a blood test while away. Please note, if you are away for more than three months, you will need to be managed by a local anticoagulation clinic. Please ensure your travel insurance provides adequate protection.
If you have had a blood clot or stroke within the last six weeks, please contact the anticoagulation clinic to discuss your travel plans.
What precautions should I take when flying?
Stay as mobile as possible while you are flying and keep well hydrated. Take your anticoagulant at the equivalent UK time where possible, allowing for changing time zones. If unsure, contact the clinic for guidance.
Can I take part in sports?
Your anticoagulation medication shouldn’t stop you from being physically active. However, please take extra care as some activities put you at higher risk of injury and/or bleeding. This includes all contact sports like football, rugby, cricket, skiing and hockey. If you are unsure, please discuss this with the anticoagulation clinic.
If you suffer a head injury, such as falling and hitting your head, or experience a blow to the head, seek medical help without delay to rule out internal bleeding which may not be immediately obvious.
Can I get a tattoo or piercing?
It is not advisable to have a tattoo or body piercing if you’re on blood-thinning medication as it can increase the risk of bleeding or infection. Please speak to your anticoagulation clinic or GP if you decide to go ahead.
What should I do if I cut or injure myself?
Usually, small cuts or scrapes will stop bleeding when pressure is applied to them. If bleeding does not stop after more than 10 minutes of first aid, seek medical attention.
If you suffer a head injury, such as falling and hitting your head, or experience a blow to the head, seek medical help without delay to rule out internal bleeding which may not be immediately obvious.
Can I take contraception, HRT or hormones?
Please speak to the anticoagulation clinic before starting these if you take warfarin or acenocoumarol. If you have had a thrombosis (blood clot) in the past, combined contraception (oestrogen and progesterone) or oral HRT (tablet) should be avoided. Alternative options are available, please discuss with your GP.
Can I become pregnant while taking anticoagulants?
Please inform us immediately when you become pregnant or if you are planning a pregnancy. Most oral anticoagulants are not safe for pregnant women or birthing people.
2. For patients taking warfarin or acenocoumarol anticoagulants
What is an INR blood test?
An international normalised ratio (INR) blood test measures how long it takes for your blood to clot. It is used to monitor blood clotting in people taking some anticoagulants. We use INR results to determine the correct dose of warfarin or acenocoumarol for you.
When will I hear from the clinic after having an INR blood test?
After your blood test, we will inform you of the new dose of warfarin or acenocoumarol you need to take (if necessary) by the end of the next working day. Result slips will be posted unless you state another preference. The dosing letter is also available to view on MyChart (called ‘AVS’). For more information about MyChart registration and support, please see MyChart section below.
We will only call patients for dose changes. Therefore, if you do not hear from the clinic, please continue to take the current dose of warfarin or acenocoumarol. If you do not receive your test results by post within five workings days, please contact the clinic (see contact details below).
How often will I need an INR blood test?
The frequency of your international normalised ratio (INR) blood tests will depend on the stability of your INR level. Some patients will require tests every one to two weeks. This time frame will be extended if your results stabilise. The maximum period between INR blood tests is 12 weeks.
When is my next INR blood test?
Your INR result, dosing instructions and next test date will be communicated to you by letter in the post. You can request that these results are emailed to you instead. It is also possible to view your next scheduled appointment for a blood test on MyChart. If you do not have MyChart, please see below for more information. If you do not receive your test results by post within five workings days, please contact the clinic. See ‘How do I book an INR blood test and where can I have it?’ below for further information.
Do I have to take the INR blood test on my scheduled day?
Always test on the day that your appointment is scheduled. Update the clinic if you are unable to test on your scheduled day as your appointment will need to be rescheduled. If you test on a different date without informing us, we may not receive your test result.
How do I book an INR blood test and where can I have it?
Once you are informed of your next test date, you will need to book your blood test online (or use walk-in service where available).
King’s College Hospital patients:
King’s College Hospital, Golden Jubilee Wing, Denmark Hill – book via Swiftqueue
Opening hours: Monday to Friday, 7.30am to 5.45pm
Tessa Jowell Health Centre, 72H East Dulwich Grove, SE22 8EY – book via Swiftqueue
Opening hours: Monday to Friday, 7.30 to 3.45pm
Princess Royal University Hospital patients:
Princess Royal University Hospital, Outpatient Department C, Ground Floor – walk-in only
Opening hours: Monday to Friday, 9am to 4pm
Beckenham Beacon Hospital, Phlebotomy Department, Ground Floor – book via Swiftqueue
Opening hours: Monday to Thursday, 7.30am to 4.30pm; Friday 8am to 4.30pm
Orpington Hospital, Phlebotomy Department, Ground Floor – book via Swiftqueue
Opening hours: Monday to Friday 7.30am to 4.30pm
Queen Mary’s Hospital, Sidcup – book via Swiftqueue
Opening hours: Monday to Thursday: 8.45am to 4.30pm, Friday: 9.15am to 1pm then 1.30pm to 4.30pm
If you do not have access to a computer or a smart phone, please contact the anticoagulation clinic for further steps.
Should I still attend my INR blood test appointment if I do not have a dosing slip?
Yes, you should still attend and explain that you take warfarin or acenocoumarol. Please take your hospital number if possible.
What should I do if I need to start a new medication?
If you are starting any new medications or supplements (including painkillers, vitamins, food supplements, natural and herbal remedies) please tell the anticoagulation clinic by phone or email, stating the name, dose and duration (if known) of the new medication. If you are due your INR blood test soon, please make a note of any medication changes on your slip. We will usually ask that you have an INR reading taken between three and five days of starting the new medication. It is a good idea to notify us when you stop a medication or change a dose too as this can also impact your INR control.
I have missed a dose of warfarin or acenocoumarol, what should I do?
If you accidently miss a dose of warfarin or acenocoumarol, take the missed dose as soon as you remember. If you do not remember until the next day, skip the missed dose and take your next dose at the usual time. Never take two doses at the same time or on the same day. Do not take extra medication unless you are instructed to by the anticoagulation clinic.
Make a note of the date that you missed your warfarin or acenocoumarol and let the clinic know on your test slip.
If you have a mechanical valve, antiphospholipid syndrome or have had a blood clot or stroke in the last three months, contact the clinic as soon as possible to update us that you have missed your dose.
What should I do if my anticoagulant medication is running low?
Always ensure you have at least a one week supply of your medication. Please contact your GP for a repeat prescription of your warfarin or acenocoumarol, allowing time for them to process the request. We can send a copy of your most recent anticoagulation slip to your GP at your request. If you need an emergency out of hours prescription contact NHS 111. Do not stop taking warfarin or acenocoumarol without speaking to the anticoagulation team.
Can I drink alcohol while taking warfarin or acenocoumarol?
Drinking alcohol can interact with warfarin and acenocoumarol to increase the INR which can increase the risk of bleeding.
Government recommendations state to drink no more than 14 units of alcohol per week, spread over at least 3 days. This equates to 6 medium glasses of wine or 6 pints of 4% beer. While there is no safe level of alcohol, not exceeding these guidelines lowers the risk of alcohol to your health.
If you exceed this quantity, please inform your anticoagulation clinic as soon as possible to arrange a blood test.
3. For patients taking apixaban, edoxaban, dabigatran or rivaroxaban anticoagulants
What should I do if I miss a dose of my medication?
If you accidently miss a dose, take the missed dose as soon as you remember. If you do not remember until the next day, skip the missed dose and take your next dose at the usual time. Never take two doses at the same time. Do not take extra medication unless you are instructed to by the anticoagulation clinic.
Do not stop taking your medication without speaking to the anticoagulation team. Please contact your GP for a repeat prescription of your medication well in advance, allowing time for them to process the request. If your GP is unable to prescribe this medication, contact the anticoagulation clinic as early as possible and we will try to resolve you prescription issue. If you need an emergency out of hours prescription contact NHS 111.
4. Information about MyChart
What is MyChart?
MyChart is an online web portal and mobile app that connects our patients to their medical information at King’s College Hospital and Guy’s and St Thomas’ NHS Foundation Trusts.
With MyChart, our patients’ health records are stored in one, easy place. You will be able to check your INR using MyChart 24 hours after testing.
Find out more information about how to access MyChart.
If you cancel your INR appointment through MyChart, please contact us at the clinic to rebook by either emailing or leaving us a voice message.
How can I get support with MyChart?
Please contact our MyChart helpdesk on 020 3299 4618 or [email protected] (Monday to Friday, 9am to 5pm)
Patient information leaflets
Title | File Size | Link |
---|---|---|
Anticoagulation and your periods | 142 KB | |
Apixaban for stroke prevention in atrial fibrillation | 114 KB | |
Apixaban for the treatment of deep vein thrombosis (DVT) or pulmonary embolism (PE) | 121 KB | |
Apixaban for the treatment of left ventricular thrombus | 119 KB | |
Deep Vein Thrombosis (DVT) | 542 KB | |
Preventing blood clots (VTE) in pregnancy | 134 KB | |
Preventing Venous Thromboembolism (VTE) | 400 KB | |
Pulmonary embolism (PE) | 336 KB |
Conditions we treat
Our service has various clinics covering the following conditions:
- thrombophilia
- antiphospholipid syndrome (APS)
- thrombocytosis
- thrombocytopaenia
- polycythaemia
- suspected bleeding disorders.
Our DVT service has become a template for innovation and good practice. Patients are referred for rapid assessment of suspected DVT and are usually seen on the day of referral in a nurse-led clinic. They are anticoagulated and undergo in-house individualised risk factor assessment, thrombophilia testing and cancer screening. Time to diagnosis is now under two hours and patients requiring treatment are home within four hours. We also operate an early-discharge PE service.
King’s Thrombosis Centre carries out extensive translational research to ensure it continues delivering a high-quality patient-centred service. Current projects include:
- defining and improving outcomes after DVT
- characterising the prothrombotic state in obesity
- optimising low molecular weight heparin regimens in pregnancy
- defining the role of thrombophilia in pregnancy loss
- characterising the prothrombotic state after stroke
- examining haemostatic abnormalities in liver disease
- learning the lessons from hospital-associated thrombosis.
For details of King’s College Hospital NHS Foundation Trust’s clinical diagnostic pathology service, visit Synnovis.
Booking a patient at King’s
Routine Referrals
GPs should refer via NHS e-referral (e-RS) wherever possible.
DVT fast-track service
We accept referrals Monday to Friday, 9am to 5pm. Tel: 07623 901 822 and quote call sign ‘DVT1’. The DVT nurse will call you back (usually within 15 minutes) to discuss whether the referral is appropriate and to give you the patient’s appointment time.
Once accepted, referrals must be made in writing. Patients can bring their referral with them or they can be emailed to [email protected]
Outside of these hours, patients should go to the emergency department with a referral letter.
Anticoagulation clinic
Call 020 3299 5553 and email the referral confirmation to: [email protected]. Calls between 9am to 4pm will be dealt with on the same day; calls after 4pm will be dealt with on the next working day.
Other thrombosis and haemostasis disorders
Contact Haematology Clinic Reception on 020 3299 5554.
Emergency Referrals
For emergency referrals, contact the individual consultants’ secretary or haematology SpR listed under the Key Clinical Staff tab.
For urgent referrals, please contact the individual consultants’ secretary listed under the Key Clinical Staff tab.
Other Queries
For advice, guidance or routine referrals, please contact the Haematology Outpatients Department.
Tel: 020 3299 3334
Key Clinical Staff
Name | Role |
---|---|
Mr Loizos Georgiou | Clinical Nurse Specialist |
Miss Jemma Johns | Consultant Obstetrician and Gynaecologist |
Dr Raj Patel | Consultant Haematologist, Coagulation |